Rubella virus infection during the first trimester can be very serious. It may lead to miscarriage, premature delivery, and death of the fetus. Babies born to a mother infected with this virus may suffer from a condition called congenital rubella syndrome. The symptoms of the syndrome include eye, ear, heart defects, microcephaly, abnormally small head, autism, and motor delay. There is no treatment available for this condition. Pregnancy women need to get vaccinated for rubella virus before pregnancy to develop immunity and avoid complications.