Study links maternal exposure to chemicals to autistic-like behaviours in children | News – Times of India Videos


Apr 01, 2021, 04:00AM ISTSource: ANI

A novel study found correlations between increased expressions of autistic-like behaviours in preschool aged children to gestational exposure to selected environmental toxicants, including metals, pesticides, polychlorinated biphenyls (PCBs), phthalates, and bisphenol-A (BPA). This population study measured the levels of 25 chemicals in blood and urine samples collected from 1,861 Canadian women during the first trimester of pregnancy. A follow-up survey was conducted with 478 participants, using the Social Responsiveness Scale (SRS) tool for assessing autistic-like behaviours in pre-school children. The researchers found that higher maternal concentrations of cadmium, lead, and some phthalates in blood or urine samples was associated with increased SRS scores, and these associations were particularly strong among children with a higher degree of autistic-like behaviours. Interestingly, the study also noted that increased maternal concentrations of manganese, trans-Nonachlor, many organophosphate pesticide metabolites, and mono-ethyl phthalate (MEP) were most strongly associated with lower SRS scores. The study’s lead author, Josh Alampi, notes that this study primarily “highlights the relationships between select environmental toxicants and increased SRS scores. Further studies are needed to fully assess the links and impacts of these environmental chemicals on brain development during pregnancy.” The results were achieved by using a statistical analysis tool, called Bayesian quantile regression, which allowed investigators to determine which individual toxicants were associated with increased SRS scores in a more nuanced way than conventional methods.

.



Source link

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.